No software or drivers are available for this product with the selected operating system. Copyright IOS Press and the authors. Operating System – Windows 7, Windows 8, Windows 8. Hum Mol Genet ; 12 The list of all available drivers for your product is shown above.

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Arrowheads indicate co-localized PSD and Vglut2, which moise thalamocortical synapses. But its a nice idea still. We also thank Stephen Grado for his help collecting activity cage data.

The role of the selective adaptor p62 and ubiquitin-like proteins in autophagy. National Center for Biotechnology InformationU.

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Keyboard – wireless Pointing Device: Kinase inhibitors modulate huntingtin cell localization and toxicity. Twitter is removing locked accounts from followers count July 12, Logitech MK Advanced – keyboard and mouse set Huntingtin associates with acidic phospholipids at the plasma membrane. Mice were examined, weighed, and then subjected to accelerating rotarod, open field, and Morris water maze testing at 3, 6, 12, 18 and 24 months of age as described [ 29 ], except that Morris water maze testing was performed 1 hour after the beginning of the dark cycle.


LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. Logitech MK – keyboard and mouse set Primary antibodies used are: The huntingtin N17 domain is a multifunctional CRM1 and Ran-dependent nuclear and cilial export signal. Internet users in Nigeria hits Hum Mol Genet ; 20 This page requires Javascript. Additionally, deletion of the Htt polyQ stretch enhances autophagy in vitro and extends lifespan in mice [ 37 ].

Drivers may be in development so please check back at a later date or visit the product homepage. N-terminal huntingtin knock-in mice: Deletion of the PRR in Htt also has no impact on embryonic development; however, it does result in spatial learning and memory deficits in month-old male mice [ mosue ].

SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes.

Neuron ; 79 2: Calnexin Abcam ; 1: We were unable to retrieve the list of drivers for your product. Potential function for the Huntingtin protein as a scaffold for selective autophagy.


Huntingtin interacts with a family of WW domain proteins. Open in a separate window. Or, view all available drivers for your product below.

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Target vector assembly, embryonic stem ES cell electroporation, and blastocyst injections were performed as described [ 36 ]. Click here for additional data file. Western blots of whole brain microsomal fractions from 6-month-old mice.

This comment form is under antispam protection. Additionally, Q HD knock-in mice have reduced numbers of thalamostriatal synapses at 1 month of age, while decreases in corticostriatal synapse numbers were not observed until 12 months of age [ 16, 17 ]. Javascript is disabled in this browser.